common_mass_offsets
The selected mass shifts used by the 'Mass-Offset-CommonPTMs' workflow in FragPipe are listed below along with Unimod annotation.
| Mass Shift (Da) | Annotation |
|---|---|
| -105.0248 | Met loss + acetaldehyde |
| -89.0299 | Met loss + Acetylation |
| -33.9877 | Dehydroalanine |
| -32.0085 | Oxidation and then loss of oxidized M side chain |
| -30.0106 | Pyrrolidinone |
| -18.0106 | Didehydrobutyrine |
| -18.0106 | Water loss |
| -17.0265 | Ammonia loss |
| -2.0157 | Didehydro |
| -2.0157 | H-2 |
| -1.007825 | Half of a disulfide bridge |
| -0.984 | Amidation |
| 0.984 | Deamidation |
| 3.9949 | Oxidation of W to Kynurenine |
| 12 | Carbon Adduct |
| 13.9793 | H-2 O1 |
| 14.0157 | Methyl |
| 15.9949 | Oxidation |
| 19.9898 | Tryptophan oxidation to hydroxykynurenin |
| 21.969392 | Replacement of 2 protons by magnesium |
| 21.9819 | Sodium |
| 23.95806 | Replacement of 3 protons by aluminium |
| 26.0157 | Acetald+26 |
| 27.9949 | Formylation |
| 28.0313 | DiMethyl |
| 28.0313 | Ethyl |
| 28.990164 | Nitrosylation |
| 29.9742 | Quinone |
| 31.972071 | Persulfide |
| 31.9898 | Dioxidation |
| 37.9469 | Calcium |
| 37.955882 | Replacement of proton by potassium |
| 42.0106 | Acetyl |
| 42.047 | TriMethylation |
| 43.0058 | Carbamyl |
| 43.9898 | Carboxylation |
| 44.985078 | Oxidation to nitro |
| 47.9847 | Trioxidation |
| 53.9193 | Fe[II] |
| 57.0215 | Carbamidomethyl |
| 58.0055 | Carboxymethylation |
| 61.9135 | Zinc |
| 61.921774 | Replacement of proton by copper |
| 68.026215 | Crotonylation |
| 70.041865 | Crotonaldehyde/Butyryl |
| 71.0371 | Propionamide |
| 71.0371 | Propionamide |
| 79.9568 | Sulfonation |
| 79.9663 | Phospho |
| 86.000394 | Malonylation |
| 100.016 | Succinylation |
| 114.042927 | ubiquitinylation residue |
| 119.004099 | Cysteinylation |
| 128.095 | Lysine not cleaved |
| 146.0579 | dHex |
| 156.1011 | Arginine not cleaved |
| 162.0528 | Hex |
| 173.051 | Acetylation+Methionine |
| 176.0321 | Glucuronyl |
| 178.0477 | Galactosyl |
| 183.035399 | Aminoethylbenzenesulfonylation |
| 189.046 | Carboxymethyl+Methionine |
| 203.0794 | HexNAc |
| 204.1878 | Farnesylation |
| 210.1984 | Myristoylation |
| 228.111 | Bacillosamine |
| 229.014009 | PyridoxalPhosphate |
| 238.2297 | Palmitoylation |
| 301.9865 | Unidentified modification of 301.9864 found in open search |
| 340.1006 | Glucosylgalactosyl |
| 349.1373 | HexNAc(1)dHex(1) |
| 365.1322 | Hex(1)HexNAc(1) |
| 365.1322 | Hex(1)HexNAc(1) |
| 406.1587 | HexNAc(2) |
| 541.06111 | ADP Ribose addition |